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que formulations  (Linseis Messgerate)
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Effect of different <t>QUE</t> <t>formulations</t> on ( a ) Escape latency time (sec) of morris water maze test and ( b ) Step-through latency time (sec) of passive avoidance test in AlCl 3 -induced Alzheimer’s disease rat model. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. Statistical significance was set at p < 0.05. * significant relative to −ve control, # significant relative to + ve control, × significant relative to QUE suspension, •significant relative to blank Tween herbosomes, ≠ significant relative to blank cocamidopropyl betaine herbosomes.
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Effect of different <t>QUE</t> <t>formulations</t> on ( a ) Escape latency time (sec) of morris water maze test and ( b ) Step-through latency time (sec) of passive avoidance test in AlCl 3 -induced Alzheimer’s disease rat model. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. Statistical significance was set at p < 0.05. * significant relative to −ve control, # significant relative to + ve control, × significant relative to QUE suspension, •significant relative to blank Tween herbosomes, ≠ significant relative to blank cocamidopropyl betaine herbosomes.
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keywords • hemostasis • hemophilia • thrombosis • thrombophilia • coagulation assays • clinical laboratory key points • thrombin generation assay tga  (Diagnostica Stago)
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Effect of different <t>QUE</t> <t>formulations</t> on ( a ) Escape latency time (sec) of morris water maze test and ( b ) Step-through latency time (sec) of passive avoidance test in AlCl 3 -induced Alzheimer’s disease rat model. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. Statistical significance was set at p < 0.05. * significant relative to −ve control, # significant relative to + ve control, × significant relative to QUE suspension, •significant relative to blank Tween herbosomes, ≠ significant relative to blank cocamidopropyl betaine herbosomes.
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Effect of different <t>QUE</t> <t>formulations</t> on ( a ) Escape latency time (sec) of morris water maze test and ( b ) Step-through latency time (sec) of passive avoidance test in AlCl 3 -induced Alzheimer’s disease rat model. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. Statistical significance was set at p < 0.05. * significant relative to −ve control, # significant relative to + ve control, × significant relative to QUE suspension, •significant relative to blank Tween herbosomes, ≠ significant relative to blank cocamidopropyl betaine herbosomes.
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Effect of different <t>QUE</t> <t>formulations</t> on ( a ) Escape latency time (sec) of morris water maze test and ( b ) Step-through latency time (sec) of passive avoidance test in AlCl 3 -induced Alzheimer’s disease rat model. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. Statistical significance was set at p < 0.05. * significant relative to −ve control, # significant relative to + ve control, × significant relative to QUE suspension, •significant relative to blank Tween herbosomes, ≠ significant relative to blank cocamidopropyl betaine herbosomes.
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tga n 1000 thermal analyzer t  (Scinco Inc)
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Effect of different <t>QUE</t> <t>formulations</t> on ( a ) Escape latency time (sec) of morris water maze test and ( b ) Step-through latency time (sec) of passive avoidance test in AlCl 3 -induced Alzheimer’s disease rat model. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. Statistical significance was set at p < 0.05. * significant relative to −ve control, # significant relative to + ve control, × significant relative to QUE suspension, •significant relative to blank Tween herbosomes, ≠ significant relative to blank cocamidopropyl betaine herbosomes.
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Effect of different QUE formulations on ( a ) Escape latency time (sec) of morris water maze test and ( b ) Step-through latency time (sec) of passive avoidance test in AlCl 3 -induced Alzheimer’s disease rat model. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. Statistical significance was set at p < 0.05. * significant relative to −ve control, # significant relative to + ve control, × significant relative to QUE suspension, •significant relative to blank Tween herbosomes, ≠ significant relative to blank cocamidopropyl betaine herbosomes.

Journal: Scientific Reports

Article Title: Herbosomal nanocarriers using natural-origin surfactants: a quercetin-based strategy for Alzheimer’s disease and oxidative-stress–driven neurodegeneration

doi: 10.1038/s41598-026-53290-0

Figure Lengend Snippet: Effect of different QUE formulations on ( a ) Escape latency time (sec) of morris water maze test and ( b ) Step-through latency time (sec) of passive avoidance test in AlCl 3 -induced Alzheimer’s disease rat model. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. Statistical significance was set at p < 0.05. * significant relative to −ve control, # significant relative to + ve control, × significant relative to QUE suspension, •significant relative to blank Tween herbosomes, ≠ significant relative to blank cocamidopropyl betaine herbosomes.

Article Snippet: Samples of pure QUE, lipoid® S75, cholesterol, their physical mixture, and the selected QUE formulations (F5&F6) were analyzed for their thermal behavior using a differential scanning calorimeter (LINSEIS STA PT-1000, China).

Techniques: Control, Suspension

Comparison between the Effect of different QUE formulations on hippocampal ( a ) TAC (mmol/ mg protein), ( b ) AChE activity (U/mg protein), ( c ) amyloid beta (Aβ 1-42), ( d ) tau protein (pg/mg protein) and ( e ) Nuclear Factor Kappa B (ng/mg protein) in AlCl3-induced Alzheimer’s model in rats. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. statistical significance was set at p < 0.05. * signicicant relative to −ve control, # signicicant relative to + ve control, × signicicant relative to QUE suspension, •signicicant relative to blank tween herbosomes , ≠ signicicant relative to blank cocamidopropyl betaine herbosomes

Journal: Scientific Reports

Article Title: Herbosomal nanocarriers using natural-origin surfactants: a quercetin-based strategy for Alzheimer’s disease and oxidative-stress–driven neurodegeneration

doi: 10.1038/s41598-026-53290-0

Figure Lengend Snippet: Comparison between the Effect of different QUE formulations on hippocampal ( a ) TAC (mmol/ mg protein), ( b ) AChE activity (U/mg protein), ( c ) amyloid beta (Aβ 1-42), ( d ) tau protein (pg/mg protein) and ( e ) Nuclear Factor Kappa B (ng/mg protein) in AlCl3-induced Alzheimer’s model in rats. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test. statistical significance was set at p < 0.05. * signicicant relative to −ve control, # signicicant relative to + ve control, × signicicant relative to QUE suspension, •signicicant relative to blank tween herbosomes , ≠ signicicant relative to blank cocamidopropyl betaine herbosomes

Article Snippet: Samples of pure QUE, lipoid® S75, cholesterol, their physical mixture, and the selected QUE formulations (F5&F6) were analyzed for their thermal behavior using a differential scanning calorimeter (LINSEIS STA PT-1000, China).

Techniques: Comparison, Activity Assay, Control, Suspension

Comparison between the Effect of different QUE formulations on Histopathological changes in Cornu Ammonis zone 1 (CA1) in hippocampus of AlCL 3 – induced AD model in rats (H&E stained section, 40X with scale bar 25 µm): ( A ) the negative control group; ( B ) AlCl3-induced AD; ( C ) QUE suspension; ( D ) blank Tween herbosomes; ( E ) blank cocamidopropyl betaine herbosomes; ( F ) F5; ( G ) F6 and ( H ) Morphometric analysis of the Mean Number Degenerated Neurons (yellow arrow, normal pyramidal neuron; red arrow, normal glial cells; black arrow, neutrophil; White arrow, shrunken darkly stained pyramidal cells; and blue arrow, vacuolated cells. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test . statistical significance was set at p < 0.05. * signicicant relative to -ve control, # signicicant relative to + ve control, × signicicant relative to QUE suspension, •signicicant relative to blank tween herbosomes, ≠ signicicant relative to blank cocamidopropyl betaine herbosomes.

Journal: Scientific Reports

Article Title: Herbosomal nanocarriers using natural-origin surfactants: a quercetin-based strategy for Alzheimer’s disease and oxidative-stress–driven neurodegeneration

doi: 10.1038/s41598-026-53290-0

Figure Lengend Snippet: Comparison between the Effect of different QUE formulations on Histopathological changes in Cornu Ammonis zone 1 (CA1) in hippocampus of AlCL 3 – induced AD model in rats (H&E stained section, 40X with scale bar 25 µm): ( A ) the negative control group; ( B ) AlCl3-induced AD; ( C ) QUE suspension; ( D ) blank Tween herbosomes; ( E ) blank cocamidopropyl betaine herbosomes; ( F ) F5; ( G ) F6 and ( H ) Morphometric analysis of the Mean Number Degenerated Neurons (yellow arrow, normal pyramidal neuron; red arrow, normal glial cells; black arrow, neutrophil; White arrow, shrunken darkly stained pyramidal cells; and blue arrow, vacuolated cells. Data are expressed as mean ± SD (n = 6) and were analyzed using one way ANOVA followed by Tukey’s post hoc test . statistical significance was set at p < 0.05. * signicicant relative to -ve control, # signicicant relative to + ve control, × signicicant relative to QUE suspension, •signicicant relative to blank tween herbosomes, ≠ signicicant relative to blank cocamidopropyl betaine herbosomes.

Article Snippet: Samples of pure QUE, lipoid® S75, cholesterol, their physical mixture, and the selected QUE formulations (F5&F6) were analyzed for their thermal behavior using a differential scanning calorimeter (LINSEIS STA PT-1000, China).

Techniques: Comparison, Staining, Negative Control, Suspension, Control